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Won Sup Lee Selected Research

Arsenic Trioxide (Trisenox)

1/2017Tetraarsenic hexoxide induces G2/M arrest, apoptosis, and autophagy via PI3K/Akt suppression and p38 MAPK activation in SW620 human colon cancer cells.
6/2015Tetraarsenic hexoxide demonstrates anticancer activity at least in part through suppression of NF-κB activity in SW620 human colon cancer cells.
5/2014Arsenic hexoxide enhances TNF-α-induced anticancer effects by inhibiting NF-κB activity at a safe dose in MCF-7 human breast cancer cells.
1/2012Tetraarsenic Hexoxide Induces Beclin-1-Induced Autophagic Cell Death as well as Caspase-Dependent Apoptosis in U937 Human Leukemic Cells.

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Won Sup Lee Research Topics

Disease

49Neoplasms (Cancer)
01/2022 - 09/2007
19Stomach Neoplasms (Stomach Cancer)
03/2022 - 08/2005
13Breast Neoplasms (Breast Cancer)
05/2021 - 03/2009
12Neoplasm Metastasis (Metastasis)
05/2020 - 04/2009
7Colonic Neoplasms (Colon Cancer)
01/2017 - 03/2009
5Carcinoma (Carcinomatosis)
03/2022 - 02/2011
5Hepatocellular Carcinoma (Hepatoma)
11/2020 - 08/2009
4Colorectal Neoplasms (Colorectal Cancer)
01/2022 - 10/2011
4Lung Neoplasms (Lung Cancer)
11/2017 - 03/2015
3Adenocarcinoma
07/2017 - 07/2015
2Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
03/2018 - 01/2014
2B-Cell Lymphoma (Lymphoma, B Cell)
07/2017 - 08/2016
2Prostatic Neoplasms (Prostate Cancer)
03/2017 - 09/2013
2Neurodegenerative Diseases (Neurodegenerative Disease)
11/2016 - 01/2013
2Infections
11/2013 - 09/2011
2Tuberous Sclerosis (Bourneville's Disease)
12/2010 - 06/2010
1Adenoma (Adenomas)
03/2022
1Sarcopenia
03/2021
1Necrosis
01/2021
1Ascites
09/2019
1Liver Cirrhosis (Hepatic Cirrhosis)
09/2019
1Peritoneal Neoplasms
09/2019
1Radiation Pneumonitis
03/2018
1Lymphoma (Lymphomas)
04/2017
1Blister (Bulla)
03/2017
1Pancreatic Neoplasms (Pancreatic Cancer)
12/2016
1Alzheimer Disease (Alzheimer's Disease)
11/2016
1Parkinson Disease (Parkinson's Disease)
11/2016
1Gastrointestinal Diseases (Functional Gastrointestinal Disorders)
07/2016
1Bronchitis
07/2016

Drug/Important Bio-Agent (IBA)

23Proteins (Proteins, Gene)FDA Link
03/2021 - 04/2009
16Anthocyanins (Anthocyanin)IBA
03/2021 - 04/2009
13FlavonoidsIBA
01/2020 - 09/2011
9Biomarkers (Surrogate Marker)IBA
03/2022 - 12/2014
8PolyphenolsIBA
01/2022 - 01/2012
5morinIBA
05/2019 - 10/2014
5AntioxidantsIBA
11/2017 - 12/2012
4DNA (Deoxyribonucleic Acid)IBA
01/2021 - 08/2009
4Cisplatin (Platino)FDA LinkGeneric
08/2020 - 11/2013
4Matrix Metalloproteinases (MMPs)IBA
05/2020 - 02/2011
4CaspasesIBA
01/2018 - 04/2009
4Arsenic Trioxide (Trisenox)FDA Link
01/2017 - 01/2012
4NF-kappa B (NF-kB)IBA
11/2016 - 10/2009
3Biological ProductsIBA
09/2019 - 09/2015
3Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
07/2016 - 01/2013
3Indicators and Reagents (Reagents)IBA
07/2015 - 07/2007
2Cyclin D1IBA
03/2022 - 11/2017
2ErbB Receptors (EGF Receptor)IBA
03/2022 - 03/2015
2CytokinesIBA
01/2022 - 11/2016
2PhytochemicalsIBA
01/2022 - 12/2014
2CateninsIBA
01/2021 - 04/2020
2Reactive Oxygen Species (Oxygen Radicals)IBA
01/2021 - 05/2019
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
05/2020 - 03/2015
2Caspase 3 (Caspase-3)IBA
08/2016 - 11/2013
2Vascular Cell Adhesion Molecule-1 (Vascular Cell Adhesion Molecule 1)IBA
07/2016 - 11/2013
2Matrix Metalloproteinase 2 (Gelatinase A)IBA
07/2016 - 08/2014
2Fluorouracil (Carac)FDA LinkGeneric
03/2015 - 08/2005
2Irinotecan (Camptosar)FDA LinkGeneric
03/2015 - 10/2011
2GemcitabineFDA Link
12/2014 - 01/2014
2Thymidine PhosphorylaseIBA
12/2014 - 09/2007
2Cyclosporine (Ciclosporin)FDA LinkGeneric
07/2014 - 06/2012
2TOR Serine-Threonine KinasesIBA
12/2010 - 06/2010
1Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2022
1Nerve Growth Factor (NGF)IBA
01/2022
1Cyclophilin AIBA
01/2021
1Propidium (Propidium Iodide)IBA
01/2021
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
01/2021
1triplex DNA (H-DNA)IBA
01/2021
1Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA
01/2021
1Annexin A5IBA
01/2021
1Golgi Matrix ProteinsIBA
01/2021
1Acridine OrangeIBA
01/2021
1Lamin Type A (Lamin A)IBA
12/2020
1JNK Mitogen-Activated Protein KinasesIBA
04/2020
1Janus Kinase 2IBA
04/2020
1naringinIBA
01/2020
1MicroRNAs (MicroRNA)IBA
09/2019
1RNA (Ribonucleic Acid)IBA
09/2019
1Carcinoembryonic AntigenIBA
09/2019
1Auranofin (Ridaura)FDA Link
05/2019
1tangeretinIBA
12/2018
1pectolinarigeninIBA
08/2018
1Cytotoxins (Cytolysins)IBA
01/2018
1scutellareinIBA
01/2018
1GelatinIBA
11/2017
1IgA receptor (protein B)IBA
04/2017
1Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
04/2017
1Ursodeoxycholic Acid (Urso)FDA LinkGeneric
03/2017
1Bile Acids and Salts (Bile Acids)IBA
03/2017
1Death Domain ReceptorsIBA
03/2017
1p38 Mitogen-Activated Protein KinasesIBA
01/2017
1AutoantibodiesIBA
12/2016

Therapy/Procedure

10Traditional Medicine (Folk Remedies)
05/2020 - 01/2012
9Therapeutics
05/2021 - 10/2011
6Drug Therapy (Chemotherapy)
07/2015 - 10/2011
2Adjuvant Chemotherapy
01/2017 - 03/2015
2Korean Traditional Medicine
06/2015 - 07/2012
2Combination Drug Therapy (Combination Chemotherapy)
03/2015 - 12/2014
1Radiotherapy
05/2021
1Chemoradiotherapy
03/2018